
Matterworks turns complex omics measurements into usable biological insights to speed research and development in life sciences. It does this via an AI-driven SaaS platform—including its Large Spectral Model (LSM) and Pyxis product—that ingests mass spectrometry and other metabolomics data and applies machine learning to standardize, interpret, and simulate metabolic environments. The platform emphasizes automation, cloud delivery, and scalability to make unstructured spectral and omics data broadly accessible to biotech teams. Typical users are biotechnology researchers and biomanufacturing groups seeking quantitative, real-time insights for experimental design and process optimization. Matterworks operates at the intersection of AI, metabolomics, and bioinformatics in a market focused on accelerating therapeutic R&D and manufacturing.

Matterworks turns complex omics measurements into usable biological insights to speed research and development in life sciences. It does this via an AI-driven SaaS platform—including its Large Spectral Model (LSM) and Pyxis product—that ingests mass spectrometry and other metabolomics data and applies machine learning to standardize, interpret, and simulate metabolic environments. The platform emphasizes automation, cloud delivery, and scalability to make unstructured spectral and omics data broadly accessible to biotech teams. Typical users are biotechnology researchers and biomanufacturing groups seeking quantitative, real-time insights for experimental design and process optimization. Matterworks operates at the intersection of AI, metabolomics, and bioinformatics in a market focused on accelerating therapeutic R&D and manufacturing.
What they do: AI-driven SaaS platform that applies self-supervised ML to mass spectrometry and metabolomics to produce actionable insights for life-science R&D
Headquarters: Somerville, Massachusetts
Founded: 2019
Notable products: Pyxis platform and Large Spectral Model (LSM)
Recent financing: Series A announced June 3, 2025 (multiple investors including Lewis & Clark Capital and OMX Ventures)
Metabolomics and mass spectrometry data interpretation for life-science R&D (discovery, toxicology, clinical development, biomanufacturing).
2019
Biotechnology Research
Series A announced on June 3, 2025; multiple participating investors reported
“Has participation from multiple institutional VCs including Lewis & Clark Capital, OMX Ventures, Germin8 Ventures, Pillar VC, Tarsadia Investments, Intermountain Ventures”
| Company |
|---|