
Mana.bio is a seed stage biotech company leveraging AI, machine learning, and nanotechnology to design novel lipid nanoparticle (LNP) drug delivery systems for targeted extrahepatic delivery of nucleic acid therapeutics and vaccines. The company focuses on gene therapy including DNA and RNA-based therapeutics, aiming to disrupt the drug delivery space by combining advanced technologies in biology and medicine. Mana.bio's proprietary AI platform discovers and optimizes customizable LNPs for tissue-specific delivery, enhancing safety, potency, and tolerability of gene therapies. The company has strategic partnerships with leading institutions like Sheba Medical Center and Ginkgo Bioworks, and has been recognized as one of Israel's top promising startups. Mana.bio is led by experienced biotech entrepreneurs and experts in drug delivery, machine learning, and software development, positioning it as an innovative player in the RNA medicine and gene therapy market.

Mana.bio is a seed stage biotech company leveraging AI, machine learning, and nanotechnology to design novel lipid nanoparticle (LNP) drug delivery systems for targeted extrahepatic delivery of nucleic acid therapeutics and vaccines. The company focuses on gene therapy including DNA and RNA-based therapeutics, aiming to disrupt the drug delivery space by combining advanced technologies in biology and medicine. Mana.bio's proprietary AI platform discovers and optimizes customizable LNPs for tissue-specific delivery, enhancing safety, potency, and tolerability of gene therapies. The company has strategic partnerships with leading institutions like Sheba Medical Center and Ginkgo Bioworks, and has been recognized as one of Israel's top promising startups. Mana.bio is led by experienced biotech entrepreneurs and experts in drug delivery, machine learning, and software development, positioning it as an innovative player in the RNA medicine and gene therapy market.
Stage: Seed
Core focus: AI-driven design of lipid nanoparticles for extrahepatic delivery of nucleic acid therapeutics
Recent disclosed seed raise: $19.5M (announced Oct 2023)
Founders / leadership: Yogev Debbi (CEO), Roy Nevo (CTO)
Drug delivery for nucleic-acid therapeutics (mRNA, DNA, oligonucleotides) and gene therapies; extrahepatic targeting of LNPs.
2021
Biotechnology
$19.5M
Round described as oversubscribed with participation from Base4 Capital, NFX, LionBird, and Technion
“Participation from prominent biotech investor Andreessen Horowitz Bio + Health and other institutional investors”