
Loto Biotech is a biotechnology platform focused on supporting the development of treatments for rare diseases, particularly those caused by dominant negative genetic mutations. Their mission is to transform the impossible into the possible by leveraging the science of siRNA. They operate out of ss17 c/o Tecnopolo D’Abruzzo.

Loto Biotech is a biotechnology platform focused on supporting the development of treatments for rare diseases, particularly those caused by dominant negative genetic mutations. Their mission is to transform the impossible into the possible by leveraging the science of siRNA. They operate out of ss17 c/o Tecnopolo D’Abruzzo.
Location: Pescara, Abruzzi, Italy (ss17 c/o Tecnopolo D'Abruzzo)
Focus: AI-driven platform to design siRNA therapies for rare genetic diseases (dominant negative mutations)
Recent funding: Seed round announced 2025-06-30
Lead investor: Scientifica Venture Capital
Rare genetic diseases, especially those caused by dominant negative mutations
Biotechnology
€600,000
Seed round announced Jun 30, 2025; press references cite €600K raised; Crunchbase lists Scientifica Venture Capital as lead.
“Scientifica Venture Capital is the lead (and sole) investor listed for the Seed round.”