
Lir Therapeutics develops engineered viral vectors to improve the safety, efficacy, and cost profile of gene therapies. The company focuses on redesigning adeno-associated virus (AAV) capsids using an AI-first platform that combines lab-in-the-loop active learning and therapeutically relevant model design to modify whole viruses. Lir operates as a biotech R&D organization targeting other biotech and gene therapy developers, applying machine learning, protein engineering, and experimental screens. Their technology stack centers on AI, AAV engineering, and gene therapy discovery workflows. The company addresses large unmet needs in gene delivery by enabling next-generation vectors for clinical and commercial use.

Lir Therapeutics develops engineered viral vectors to improve the safety, efficacy, and cost profile of gene therapies. The company focuses on redesigning adeno-associated virus (AAV) capsids using an AI-first platform that combines lab-in-the-loop active learning and therapeutically relevant model design to modify whole viruses. Lir operates as a biotech R&D organization targeting other biotech and gene therapy developers, applying machine learning, protein engineering, and experimental screens. Their technology stack centers on AI, AAV engineering, and gene therapy discovery workflows. The company addresses large unmet needs in gene delivery by enabling next-generation vectors for clinical and commercial use.
Headquarters: London (LBIC, 2 Royal College St)
Focus: AI-driven redesign of AAV viral vectors for gene therapy
Platform: nAAVigator® lab-in-the-loop AI platform
Founded: 2024
Early funding: Pre-Seed round announced Sep 1, 2024 (Fly Ventures lead; Amino Collective investor)
Gene therapy vector engineering (AAV capsid design for dose reduction, targeting, and immune evasion).
2024
Biotechnology
Investors listed include Fly Ventures (lead) and Amino Collective.
“Fly Ventures; Amino Collective”