Leash Biosciences

Leash Biosciences builds a large experimental dataset and ML models to improve how small molecules are designed for specific protein targets. They generate high-throughput protein-molecule interaction data using automated in-house protein production and DNA-encoded chemical library screening, and apply machine learning to design and prioritize novel compounds. The company reports measuring billions of interactions and designing millions of candidate molecules to close the data gap in medicinal chemistry. Leash operates as a data-driven drug design platform (B2B) serving biopharma and research partners with software and experimental workflows that accelerate early discovery. They focus on scalable measurement across many protein targets and collaborative partnerships to translate model insights into new therapeutic programs.