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HotSpot Therapeutics
HotSpot Therapeutics discovers allosteric medicines that modulate natural regulatory hotspots on proteins to treat cancer, autoimmune and other diseases. The company uses its proprietary Smart…
HotSpot Therapeutics
HotSpot Therapeutics discovers allosteric medicines that modulate natural regulatory hotspots on proteins to treat cancer, autoimmune and other diseases. The company uses its proprietary Smart…
TL;DR
Founded: 2017
Headquarters: Boston, Massachusetts
Focus: Allosteric small-molecule therapies for cancer and autoimmune disease
Proprietary platform: Smart Allostery / SpotFinder
Clinical asset: HST-1011 (oral allosteric CBL-B inhibitor) in clinical development
Total funding (reported): USD 210,000,000
Company Overview
Problem Domain
Drug discovery and development for oncology and immunology using allosteric modulation of proteins.
Founded
2017
Industry
Biotechnology Research
Tech Stack
Funding Track Record
USD 45,000,000
USD 65,000,000
USD 100,000,000
Investor Signal
“Atlas Venture; Sofinnova Partners; S.R. One; Pivotal bioVenture Partners; Tekla Capital Management; MRL Ventures Fund; Solasta Ventures; Brace Pharma; LSP; B Capital; Monashee; CaaS Capital Management; Revelation Partners”
Founders
What we do
Join the Team
Startup jobs. A lot of them.
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