
Exogene is a techbio startup leveraging deep learning to discover innovative TCR-based therapies for cancer treatment. By harnessing the natural ability of human T-cells to eliminate diseased cells, Exogene's generative AI platform comprehensively mines the TCR sequence space to identify novel, high-affinity, and non-cross-reactive TCRs against shared cancer targets. This approach addresses the challenge of finding safe and effective TCRs, positioning Exogene as a leader in the development of TCR-based immunotherapies. The company aims to accelerate the discovery process, making it faster and more cost-effective, thereby enhancing its market position in the competitive biotech landscape.

Exogene is a techbio startup leveraging deep learning to discover innovative TCR-based therapies for cancer treatment. By harnessing the natural ability of human T-cells to eliminate diseased cells, Exogene's generative AI platform comprehensively mines the TCR sequence space to identify novel, high-affinity, and non-cross-reactive TCRs against shared cancer targets. This approach addresses the challenge of finding safe and effective TCRs, positioning Exogene as a leader in the development of TCR-based immunotherapies. The company aims to accelerate the discovery process, making it faster and more cost-effective, thereby enhancing its market position in the competitive biotech landscape.
What they do: AI-enabled discovery and engineering of T-cell receptors (TCRs) for cancer therapies
Founded: 2019
Headquarters: Oxford, United Kingdom
Notable funding: $2.0M seed (Apr 2022)
Team size (approx.): 14 employees
TCR discovery and engineering for cancer immunotherapies (solid tumours)
2019
Biotechnology
2,000,000 USD
Seed round to develop AI-enabled TCR discovery platform; participating investors included R42 Group, Jude Gomila, Nadav Rosenberg, Stefano Bernardi, KQ Labs, Entrepreneur First, Sigmas Group and other angels.
“Participated by specialist VC and angel investors focused on deep tech and biotech”