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ENSEM Therapeutics is a drug discovery and development company focused on oncology precision medicines using its proprietary Kinetic Ensemble® platform. The company integrates AI, computational…

ENSEM Therapeutics is a drug discovery and development company focused on oncology precision medicines using its proprietary Kinetic Ensemble® platform. The company integrates AI, computational…
Headquarters: Waltham, Massachusetts
Founded: 2021
Focus: Small‑molecule oncology precision medicines using Kinetic Ensemble platform
Lead program: ETX-636 (oral allosteric PI3Kα inhibitor/degrader) in Phase 1/2
Reported funding: $120M total raised (company presentation, Jan 2025)
Oncology; discovering ligands for difficult‑to‑drug protein targets by uncovering cryptic binding pockets.
2021
Biotechnology
$67,000,000
Crunchbase funding‑round entry references a $67M Series A.
$120,000,000
Company presentation (Jan 2025) states $120M raised since inception (equity + nondilutive funding).
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