
Digistain is a UK-based company that has developed a transformational breast cancer biomarker analytics technology. Their Digistain Test is an MHRA-cleared, UKCA-marked solution that assesses the risk of recurrence in breast cancer patients after surgery. It provides a 10-year risk score, guiding clinicians on adjuvant chemotherapy decisions. Unlike traditional methods that are slow and expensive, Digistain offers a rapid, AI-enabled solution delivering results in under an hour at a fraction of the cost. It is designed for Stage I-II, HER2-, ER+ breast cancer patients with up to 3 positive lymph nodes. The company was founded by Dr. Hemmel Amrania, who patented a novel method for grading tumor biopsies. Digistain aims to eliminate inequalities in breast cancer care by making accurate, timely, and affordable predictive tests accessible.

Digistain is a UK-based company that has developed a transformational breast cancer biomarker analytics technology. Their Digistain Test is an MHRA-cleared, UKCA-marked solution that assesses the risk of recurrence in breast cancer patients after surgery. It provides a 10-year risk score, guiding clinicians on adjuvant chemotherapy decisions. Unlike traditional methods that are slow and expensive, Digistain offers a rapid, AI-enabled solution delivering results in under an hour at a fraction of the cost. It is designed for Stage I-II, HER2-, ER+ breast cancer patients with up to 3 positive lymph nodes. The company was founded by Dr. Hemmel Amrania, who patented a novel method for grading tumor biopsies. Digistain aims to eliminate inequalities in breast cancer care by making accurate, timely, and affordable predictive tests accessible.
Product: Digistain — an MHRA-cleared, UKCA-marked infrared spectroscopy and AI-enabled tumour-profiling test for early-stage ER+, HER2- breast cancer
Clinical validation: Published clinical validation using samples from 801 early-stage HR+ breast cancer patients
Speed & cost: Delivers results in under an hour and is positioned as lower-cost than genomic assays
Regulatory status: MHRA-cleared and UKCA-marked
Founding year: 2020
Notable investors: Y Combinator, Acacia Venture Capital Partners, Sofia Angels Ventures
Predicting breast cancer recurrence risk to inform adjuvant chemotherapy decisions for early-stage ER+, HER2- patients.
2020
Biotechnology
Participation in Y Combinator accelerator; reported $125k associated with YC support
“Y Combinator, Acacia Venture Capital Partners, Sofia Angels Ventures”