
CrystalsFirst is a service provider in biotech and pharma, offering advanced drug discovery and high-performance structural biology services. Their mission is to unlock chemical matter for protein targets using a "structural data first" approach. Their MAGNET platform integrates structural biology and generative AI to identify druggable binding pockets and design molecules for challenging targets, accelerating the discovery of novel therapeutics. They have a proven track record with global pharma and biotech companies, focusing on solving complex drug discovery challenges through their expertise in crystallographic fragment screening, co-structure determination, and integrated drug research from early discovery to preclinical development. The company has expanded its operations and offers flexible business models, emphasizing a strong scientific foundation and customer-centric approach.

CrystalsFirst is a service provider in biotech and pharma, offering advanced drug discovery and high-performance structural biology services. Their mission is to unlock chemical matter for protein targets using a "structural data first" approach. Their MAGNET platform integrates structural biology and generative AI to identify druggable binding pockets and design molecules for challenging targets, accelerating the discovery of novel therapeutics. They have a proven track record with global pharma and biotech companies, focusing on solving complex drug discovery challenges through their expertise in crystallographic fragment screening, co-structure determination, and integrated drug research from early discovery to preclinical development. The company has expanded its operations and offers flexible business models, emphasizing a strong scientific foundation and customer-centric approach.
Founded: 2018
Headquarters: Marburg / Gladenbach, Germany
Core offering: Structure-first small-molecule drug discovery (MAGNET platform)
Team size (reported): ≈21 employees
Notable supporters: Hessen Kapital I, EXIST, MassChallenge, VentureOut
Small-molecule drug discovery for challenging protein targets using structural biology and AI.
2018
Biotechnology
Seed round with Hessen Kapital I listed as lead (date reported March 14, 2018).
Non-equity assistance/support program entry reported on August 1, 2022.
“Hessen Kapital I, EXIST, MassChallenge, VentureOut”