
Crane Biosciences develops gene and RNA therapies that use red blood cell–derived nanoparticles to deliver treatments while avoiding immune detection. The company engineers RBC-derived nanoparticles (RBCNPs) to encapsulate RNA payloads and reduce immune system reactions, and applies AI to design and optimize candidates. It operates as a biotech therapeutics developer combining nanotechnology, RNA therapeutics, and computational drug‑discovery tools. Based at Imperial College London with academic and accelerator partners, Crane advances programs for genetic and other hard-to-treat diseases toward clinical development.

Crane Biosciences develops gene and RNA therapies that use red blood cell–derived nanoparticles to deliver treatments while avoiding immune detection. The company engineers RBC-derived nanoparticles (RBCNPs) to encapsulate RNA payloads and reduce immune system reactions, and applies AI to design and optimize candidates. It operates as a biotech therapeutics developer combining nanotechnology, RNA therapeutics, and computational drug‑discovery tools. Based at Imperial College London with academic and accelerator partners, Crane advances programs for genetic and other hard-to-treat diseases toward clinical development.
Core technology: Red blood cell-derived nanoparticles (RBCNPs) for RNA/gene delivery
Clinical focus: Gene and RNA therapies targeting genetic and hard-to-treat diseases
Funding: Pre-Seed announced 2024-06-03; lead investor: Norrsken Accelerator
Founded: 2022
Research base: Based at Imperial College London with academic and accelerator partners
Delivery of RNA and gene therapies for diseases caused by genetic mutations and other hard-to-treat conditions.
2022
Biotechnology
125000 USD
“Norrsken Accelerator”