
Biotx.ai is an AI-driven causal modeling company focused on drug discovery and development. They leverage a proprietary causal genome dataset to map genomic loci to downstream effects on biomarker levels and disease risk. This enables them to screen biomarkers, predict drug efficacy, and identify top indications for drug assets. Their technology has helped biopharma partners secure Series A and B funding, enabled CROs to close deals for clinical trials, and led to six drug asset out-licensings. Notable clients include Simbec-Orion, Refoxy Pharma, and Samsara Therapeutics, who have seen significant benefits such as new contracts worth $35M and securing €20M in investment.

Biotx.ai is an AI-driven causal modeling company focused on drug discovery and development. They leverage a proprietary causal genome dataset to map genomic loci to downstream effects on biomarker levels and disease risk. This enables them to screen biomarkers, predict drug efficacy, and identify top indications for drug assets. Their technology has helped biopharma partners secure Series A and B funding, enabled CROs to close deals for clinical trials, and led to six drug asset out-licensings. Notable clients include Simbec-Orion, Refoxy Pharma, and Samsara Therapeutics, who have seen significant benefits such as new contracts worth $35M and securing €20M in investment.
Focus: AI-driven causal modeling for drug discovery and biomarker-led precision medicine
Headquarters: Potsdam/Berlin, Germany
Founding year: 2017
Notable capabilities: Large-scale Mendelian randomization, colocalization, synthetic clinical trials using ~2M genomes (company claim)
Team / leadership: Founder: Jörn Klinger; Senior leader: Marco Schmidt
Drug discovery, target validation, biomarker discovery, and clinical-trial design using causal genomics and AI.
2017
Biotechnology
Company reports project-level and regional/EU grant support (European Regional Development Fund and related Brandenburg/ESF programs) rather than disclosed venture rounds.
“Harald Pinger identified as first major investor; Hoxton Ventures represented on board via Hussein Kanji; additional investors listed in profiles include Oxonian Ventures and PROTOCOL.”