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Affinia Therapeutics is a pioneering company in gene therapy, focusing on developing innovative adeno-associated virus (AAV) vectors to treat rare and prevalent diseases. Utilizing their proprietary…

Affinia Therapeutics is a pioneering company in gene therapy, focusing on developing innovative adeno-associated virus (AAV) vectors to treat rare and prevalent diseases. Utilizing their proprietary…
Founded: 2019
Headquarters: Waltham, Massachusetts
Focus: Rationally designed AAV gene therapies (cardiotropic and CNS-targeting)
Lead program: AFTX-201 for BAG3-associated dilated cardiomyopathy
Total disclosed funding: USD 210,000,000
Recent round: Series C $40M (announced 2025-10-07)
Gene therapy for cardiac and central nervous system diseases, including BAG3-associated dilated cardiomyopathy.
2019
Biotechnology Research
USD 60,000,000
Series A announced as oversubscribed; participation included F-Prime Capital and NEA.
USD 40,000,000
Series C included new investor Eli Lilly & Company and participation from existing investors.
“Backed by multiple venture and strategic investors including NEA, Atlas Venture, F-Prime, NEA, Eli Lilly, GV, Alexandria Venture Investments, Perceptive Advisors and others”
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