
AcuraStem is a patient-based biotechnology company focused on developing innovative treatments for neurodegenerative diseases like ALS and FTD. Utilizing their proprietary iNeuroRx® platform, they create individual patient models to better understand disease mechanisms and develop effective therapies. Their approach aims to overcome the limitations of traditional animal models, leading to treatments that are broadly effective across various patient subtypes. With a strong team of experts and a growing pipeline, AcuraStem is positioned to make significant advancements in the field of neurodegenerative disease treatment.

AcuraStem is a patient-based biotechnology company focused on developing innovative treatments for neurodegenerative diseases like ALS and FTD. Utilizing their proprietary iNeuroRx® platform, they create individual patient models to better understand disease mechanisms and develop effective therapies. Their approach aims to overcome the limitations of traditional animal models, leading to treatments that are broadly effective across various patient subtypes. With a strong team of experts and a growing pipeline, AcuraStem is positioned to make significant advancements in the field of neurodegenerative disease treatment.
Focus: Patient-based biotech developing therapies for ALS and FTD
Platform: Proprietary iNeuroRx® patient-derived disease-modeling platform
Lead program / deal: AS-202 (PIKFYVE-targeting ASO); license agreement with Takeda
Funding highlights: Multiple grant awards including ~$7M (NIH/DOD) and a $4M CIRM grant (Sep 3, 2024)
Neurodegenerative disease therapeutics (ALS, FTD)
2016
Biotechnology
4000000
Grant to advance UNC13A program
Nearly $7M in grant funding announced to support ALS/FTD programs
MDA Venture Philanthropy grant (~$300,000 over two years) for preclinical ALS work