
Pentagrit is a pre-clinical Contract Research Organization (CRO) specializing in in vivo efficacy services using zebrafish as a research model. They offer services including phenotype rescue, biomarker identification, pharmacokinetics (PK), and toxicology screening. Pentagrit leverages zebrafish for their rapid development, genetic similarity to humans, and transparency, enabling real-time imaging and detailed profiling. Their offerings include specialized zebrafish lines, research models, and a discovery platform with ML applications. The company emphasizes their ability to cover 90% of human druggable targets with knockout models, providing strong evidence for compound activity. Pentagrit conducts over 120 annual studies globally and aims to deliver reliable PK data for preclinical drug development, accelerating discovery timelines.

Pentagrit is a pre-clinical Contract Research Organization (CRO) specializing in in vivo efficacy services using zebrafish as a research model. They offer services including phenotype rescue, biomarker identification, pharmacokinetics (PK), and toxicology screening. Pentagrit leverages zebrafish for their rapid development, genetic similarity to humans, and transparency, enabling real-time imaging and detailed profiling. Their offerings include specialized zebrafish lines, research models, and a discovery platform with ML applications. The company emphasizes their ability to cover 90% of human druggable targets with knockout models, providing strong evidence for compound activity. Pentagrit conducts over 120 annual studies globally and aims to deliver reliable PK data for preclinical drug development, accelerating discovery timelines.